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“jwh 073”的搜索结果

产品 1 到 50 共 127个

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  1. XL184 free base (Cabozantinib)
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    XL184 free base (Cabozantinib)

    Catalog No. A10996
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    VEGFR 抑制剂
    XL184 free base (Cabozantinib)是设计用来抑制多种受体酪氨酸激酶（特别是MET和VEGFR2）的小分子。 了解更多
  2. PLX4032 (Vemurafenib)
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    PLX4032 (Vemurafenib)

    Catalog No. A10739
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    Raf 抑制剂
    PLX4032(Vemurafenib)也称为RG7204，Vemurafenib，R7204，RO5185426。PLX4032是B-raf抑制剂，IC50为44 nM。 了解更多
  3. PIK-93
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    PIK-93

    Catalog No. A10731
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    PI3K 抑制剂
    PIK-93是第一个有效的，人工合成的PI4K(PI4KIIIβ)抑制剂，IC50为19 nM；抑制PI3Kα，IC50为39 nM。 了解更多
  4. CP-690550 (Tofacitinib citrate)
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    CP-690550 (Tofacitinib citrate)

    Catalog No. A10241
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    JAK3 抑制剂
    CP-690550 (Tofacitinib citrate)是口服的高选择性Janus激酶（JAK）酶抑制剂。 了解更多
  5. Pimobendan (Vetmedin)
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    Pimobendan (Vetmedin)

    Catalog No. A10733
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    PDE 抑制剂
    Pimobendan (Vetmedin)是一种钙增敏剂，具有正性肌力和血管舒张作用。它也是磷酸二酯酶III（PDE3）的选择性抑制剂。 了解更多
  6. GSK256066
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    GSK256066

    Catalog No. A11073
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    PDE 抑制剂
    GSK256066是PDE4的极高亲和力和选择性抑制剂，它以相等的亲和力抑制PDE4亚型A-D，并具有很高的HARBS（高亲和力利普兰结合位点）比率（> 17）。 了解更多
  7. Nitisinone
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    Nitisinone

    Catalog No. A11093
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    HPPD 抑制剂
    Nitrisinone是一种竞争性抑制剂，可逆地抑制4-羟基苯基丙酮酸氧化酶（双加氧酶）。 了解更多
  8. PIK-90
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    PIK-90

    Catalog No. A10730
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    PI3K 抑制剂
    PIK-90是一种合成的磷酸肌醇3激酶（PI3K）抑制剂，对于p110α，β，γ和δ亚型的IC50值（nM）为11、350、18和58，mTOR活性低。 了解更多
  9. Pimecrolimus
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    Pimecrolimus

    Catalog No. A10732
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    Pimecrolimus是一种天然的子囊霉素大内酰胺，可与大亲霉素12（FKBP-12）结合并抑制钙调神经磷酸酶和脯氨酰异构酶（旋转异构酶）。 了解更多
  10. Piperine (1-Piperoylpiperidine)
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    Piperine (1-Piperoylpiperidine)

    Catalog No. A10734
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    Piperine (1-Piperoylpiperidine)是生物碱，它与黑胡椒碱（胡椒碱的异构体）一起对黑胡椒和long胡椒具有刺激性。它也已用于某些形式的传统医学和作为杀虫剂。 了解更多
  11. Safinamide Mesylate (FCE28073)
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    Safinamide Mesylate (FCE28073)

    Catalog No. A10818
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    MAO 抑制剂
    Safinamide Mesylate是沙芬酰胺的甲磺酸盐，可选择性和可逆地抑制MAO-B，IC50为0.45μM。 了解更多
  12. Amphotericin B
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    Amphotericin B

    Catalog No. A10073
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    Amphotericin B是来自链霉菌属的多烯抗真菌抗生素。Amphotericin B诱导K+泄漏，这与其致死作用是分开的，正如在人类红细胞中所证明的，这是由于对Na+/K+泵的抑制作用所致。 了解更多
  13. Bay 65-1942
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    Bay 65-1942

    Catalog No. A11339
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    IKKβ 抑制剂
    Bay 65-1942是选择性靶向IKKβ激酶活性的ATP竞争性抑制剂。 了解更多
  14. Bay 65-1942 HCl
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    Bay 65-1942 HCl

    Catalog No. A11338
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    IKKβ kinase 抑制剂
    Bay 65-1942 HCl是选择性靶向IKKβ激酶活性的ATP竞争性抑制剂。 了解更多
  15. PF-04554878 (Defactinib)
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    PF-04554878 (Defactinib)

    Catalog No. A11929
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    FAK 抑制剂
    PF-04554878 (Defactinib)是一种新型FAK激酶抑制剂，可降低胰腺神经内分泌肿瘤细胞的生长并诱导其凋亡。 了解更多
  16. GDC-0349
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    GDC-0349

    Catalog No. A11443
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    mTOR 抑制剂
    GDC-0349是一种有效的，选择性的，ATP竞争性的mTOR抑制剂，Ki为3.8 nM，比作用于PI3Kα和其他266种激酶的抑制效果高790倍。 了解更多
  17. Pirarubicin
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    Pirarubicin

    Catalog No. A10735
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    Topoisomerase II 抑制剂
    Pirarubicin是蒽环类抗肿瘤阿霉素的类似物。插入DNA中并与Topo II（拓扑异构酶II）相互作用并抑制DNA复制。 了解更多
  18. Piroxicam (Feldene)
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    Piroxicam (Feldene)

    Catalog No. A10736
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    COX 抑制剂
    Piroxicam (Feldene)是前列腺素合成的有效抑制剂，并且是Cox-1和Cox-2抑制剂。 了解更多
  19. Pitavastatin calcium (Livalo)
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    Pitavastatin calcium (Livalo)

    Catalog No. A10737
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    HMG-CoA reductase 抑制剂
    Pitavastatin calcium (Livalo)是HMGCR（HMG-CoA还原酶）酶的竞争性抑制剂，可降低LDL胆固醇的合成。 了解更多
  20. Pizotifen malate
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    Pizotifen malate

    Catalog No. A10738
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    Pizotifen malate是苯并环庚噻吩的衍生物，是一种三环化合物，被发现是有效的SR-2受体活性抑制剂。 了解更多
  21. Isochlorogenic acid B
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    Isochlorogenic acid B

    Catalog No. A12073
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    Isochlorogenic acid B来自金银花的花蕾。 了解更多
  22. Clemizole
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    Clemizole

    Catalog No. A13073
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    H1 histamine receptor 拮抗剂.
    Clemizole是H1组胺受体拮抗剂。 了解更多
  23. Sivelestat sodium salt
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    Sivelestat sodium salt

    Catalog No. A14073
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    Neutrophil elastase 抑制剂
    Sivelestat sodium salt是一种选择性白细胞弹性蛋白酶抑制剂（IC50 = 44 nM），在一系列其他蛋白酶中均无活性。它在体外抑制NF-κB活化和LTB4诱导的中性粒细胞转运。 了解更多
  24. LDC000067
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    LDC000067

    Catalog No. A14273
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    CDK 抑制剂
    LDC000067是一种高选择性CDK9抑制剂。 了解更多
  25. Rauwolscine
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    Rauwolscine

    Catalog No. A13426
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    α2-adrenergic receptor 拮抗剂
    Rauwolscine是一种天然生物碱，具有选择性和可逆性α2肾上腺素能受体拮抗剂(Ki = 12 nM)。 了解更多
  26. Saikosaponin C
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    Saikosaponin C

    Catalog No. A14571
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    Saikosaponin C诱导内皮细胞生长，迁移和毛细管形成。 了解更多
  27. Demethylzeylasteral
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    Demethylzeylasteral

    Catalog No. A14745
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    Demethylzeylasteral对雌二醇葡萄糖醛酸化反应有剂量依赖性的抑制作用。 了解更多
  28. Garcinone D
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    Garcinone D

    Catalog No. A14800
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    Garcinone D是一种来自山竹的天然呫吨酮 (xanthone)，可促进C17.2神经干细胞的增殖。 Garcinone D以浓度和时间依赖的方式增加磷酸化信号转导子和转录激活因子3 (p-STAT3)，Cyclin D1和核因子红细胞2相关因子 (Nrf2)，血红素加氧酶-1 (HO-1) 蛋白水平。 了解更多
  29. E-3810
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    E-3810

    Catalog No. A15073
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    VEGFR/FGFR 抑制剂
    E-3810是一种有效且选择性的VEGF和FGF受体双重抑制剂，对VEGFR-1，VEGFR-2，VEGFR-3，FGFR-1和VEGF的IC50值分别为7nM，25nM，10nM，17.5nM和82.5nM。FGFR-2。 了解更多
  30. mTOR inhibitor (mTOR-IN-1)
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    mTOR inhibitor (mTOR-IN-1)

    Catalog No. A15175
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    mTOR 抑制剂
    mTOR inhibitor (mTOR-IN-1)是mTOR的有效且选择性的ATP竞争性抑制剂，Ki为1.5 nM。 了解更多
  31. HG6-64-1
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    HG6-64-1

    Catalog No. A16022
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    B-Raf 抑制剂
    HG6-64-1是有效的选择性B-Raf和突变B-Raf抑制剂；更多信息可以在专利WO 2011090738中找到。 了解更多
  32. (+)-ITD 1
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    (+)-ITD 1

    Catalog No. A16073
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    TGF-β 抑制剂
    (+)-ITD 1 是ITD-1的拆分对映异构体，与外消旋ITD-1相比，其TGF-β抑制作用（?400 nM）增加了2倍以上，在心脏发生方面增加了1.3倍。 了解更多
  33. KJ Pyr 9
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    KJ Pyr 9

    Catalog No. A16324
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    MYC 抑制剂
    KJ Pyr 9是来自Krhnke吡啶库的MYC的新型小分子抑制剂KJ-Pyr-9。 了解更多
  34. GROEL (27-573) Human
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    GROEL (27-573) Human

    Catalog No. AP0073
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    GroEL (HSP60) (27-573 a.a.) Human Recombinant 了解更多
  35. FSBP Human
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    FSBP Human

    Catalog No. AP0704
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    Fibrinogen Silencer Binding Protein Human Recombinant 了解更多
  36. NMB Human
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    NMB Human

    Catalog No. AP0730
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    Neuromedin B Human Recombinant 了解更多
  37. ASPSCR1 Human
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    ASPSCR1 Human

    Catalog No. AP0731
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    Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 Human Recombinant 了解更多
  38. S100A12 Human
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    S100A12 Human

    Catalog No. AP0732
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    S100 Calcium Binding Protein A12 Human Recombinant 了解更多
  39. TEN1 Human
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    TEN1 Human

    Catalog No. AP0733
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    TEN1 Human Recombinant 了解更多
  40. PHF5A Human
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    PHF5A Human

    Catalog No. AP0734
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    PHD Finger Protein 5A Human Recombinant 了解更多
  41. FBXO6 Human
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    FBXO6 Human

    Catalog No. AP0735
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    F-Box Protein 6 Human Recombinant 了解更多
  42. TEF Human
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    TEF Human

    Catalog No. AP0736
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    Thyrotrophic Embryonic Factor Human Recombinant 了解更多
  43. MBP E.coli
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    MBP E.coli

    Catalog No. AP0737
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    Myelin Basic Protein E.coli Recombinant 了解更多
  44. STOM Human
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    STOM Human

    Catalog No. AP0738
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    Stomatin Human Recombinant 了解更多
  45. PPP1R11 Human
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    PPP1R11 Human

    Catalog No. AP0739
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    Protein Phosphatase 1, Regulatory Subunit 11 Human Recombinant 了解更多
  46. ATP5F1 Human
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    ATP5F1 Human

    Catalog No. AP1073
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    Synthase Transporting Mitochondrial Fo Complex B1 Human Recombinant 了解更多
  47. HPR Human
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    HPR Human

    Catalog No. AP1121
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    Haptoglobin-Related Protein Human Recombinant 了解更多
  48. Haptoglobin (19-347) Human
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    Haptoglobin (19-347) Human

    Catalog No. AP1133
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    Haptoglobin (19-347 a.a) Human Recombinant 了解更多
  49. CRYGC Human
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    CRYGC Human

    Catalog No. AP0291
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    Crystallin, Gamma C Human Recombinant 了解更多
  50. ASGR2 Human
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    ASGR2 Human

    Catalog No. AP0466
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    Asialoglycoprotein Receptor 2 Human Recombinant 了解更多

产品 1 到 50 共 127个

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