“Akt Inhibitor”的搜索结果

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  1. AKT Kinase Inhibitor

    Catalog No. A11285
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    Akt kinase inhibitor
    AKT Kinase Inhibitor is an Akt kinase inhibitor with anti-tumor activity. 了解更多
  2. AKT-IN-1

    Catalog No. A21009
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    AKT inhibitor
    AKT-IN-1 is an allosteric AKT inhibitor with an IC50 of 1.042 μM. 了解更多
  3. AKT inhibitor VIII (AKTI-1/2)

    Catalog No. A11286
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    AKT 抑制剂
    AKT inhibitor VIII (AKTI-1/2)是一种细胞可渗透且可逆的喹喔啉化合物,在体外激酶测定中,该化合物有效和选择性地抑制Akt1/Akt2活性(对于Akt1,Akt2和Akt3,IC50分别为58 nM,210 nM和2.12μM)。 了解更多
  4. AKT-IN-2

    Catalog No. A20147
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    AKT inhibitor
    AKT-IN-2 is a potent, selective and orally bioavailable AKT inhibitor with an IC50 of 5 nM for AKT1. 了解更多
  5. PF-AKT400

    Catalog No. A21991
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    Akt inhibitor
    PF-AKT400 is a broadly selective, potent, ATP-competitive Akt inhibitor, displays 900-fold greater selectivity for PKBα (IC50=0.5 nM) than PKA (IC50=450 nM). 了解更多
  6. Akt-l-1

    Catalog No. A12435
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    AKT1 抑制剂
    Akt-I-1是Akt1(IC50为4.6 μM)的特异性抑制剂,不抑制AKT2或AKT3。 了解更多
  7. AdScreen™ PI3K/Akt/mTOR Inhibitor Compound Library

    Catalog No. CPL002
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  8. Ipatasertib dihydrochloride

    Catalog No. A21734
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    pan-Akt inhibitor
    Ipatasertib dihydrochloride (GDC-0068 dihydrochloride) is a highly selective pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 5/18/8 nM, 620-fold selectivity over PKA. 了解更多
  9. Solenopsin

    Catalog No. A21087
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    ATP-competitive AKT inhibitor
    Solenopsin is an ATP-competitive AKT inhibitor with IC50 value of 10 μM . 了解更多
  10. OSU-T315

    Catalog No. A20870
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    ILK inhibitor
    OSU-T315 (ILK-IN-1) is a small Integrin-linked kinase (ILK) inhibitor with an IC50 of 0.6 μM, inhibiting PI3K/AKT signaling by dephosphorylation of AKT-Ser473 and other ILK targets (GSK-3β and myosin light chain). 了解更多
  11. Isobavachalcone

    Catalog No. A11453
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    Akt inhibitor
    Isobavachalcone (Corylifolinin) is derived from Psoralea corylifolia Linn. and is a potent inhibitor of Akt signaling pathway, which induces apoptosis in human cancer cells (Inhibits OVCAR-8 cell growth with an IC50 value of 7.92 μM). 了解更多
  12. Borussertib

    Catalog No. A13364
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    Akt inhibitor
    Borussertib is a covalent-allosteric and first-in-class inhibitor of protein kinase Akt, with an IC50 of 0.8 nM and a Ki of 2.2 nM for Aktwt. 了解更多
  13. API-1

    Catalog No. A22093
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    Akt inhibitor
    API-1 (NSC 177223) is a potent inhibitor of Akt that induces GSK3-dependent, β-TrCP- and FBXW7-mediated Mcl-1 degradation, resulting in induction of apoptosis. 了解更多
  14. Miransertib hydrochloride

    Catalog No. A22376
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    Akt inhibitor
    Miransertib hydrochloride (ARQ-092 hydrochloride) is a potent, orally active, selective and allosteric Akt inhibitor with IC50s of 2.7 nM, 14 nM and 8.1 nM for Akt1, Akt2, Akt3, respectively. 了解更多
  15. 10-DEBC HCl

    Catalog No. A13590
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    AKT/PKB 抑制剂?
    10-DEBC HCl是Akt/PKB的选择性抑制剂。它抑制IGF-1刺激的磷酸化和Akt的激活(在2.5μM时完全抑制),抑制mTOR,p70 S6激酶的下游激活。 了解更多
  16. WAY-600

    Catalog No. A11188
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    mTOR 抑制剂
    WAY-600是一种有效的,ATP竞争性的,选择性的mTOR抑制剂,IC50为9 nM;抑制mTORC1/P-S6K(T389)和mTORC2/P-AKT(S473),但不抑制P-AKT(T308);作用于mTOR比作用于PI3Kα(>100倍)和PI3Kγ(>500倍)选择性高。 了解更多
  17. WYE-687

    Catalog No. A11187
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    mTOR 抑制剂
    WYE-687是雷帕霉素(mTOR)哺乳动物靶标的新型ATP竞争性和选择性抑制剂,IC50为7 nM;抑制mTORC1/pS6K(T389)和mTORC2/P-AKT(S473),但不抑制P-AKT(T308),作用于mTOR比作用于PI3Kα(>100倍)和PI3Kγ(>500倍)选择性高。 了解更多
  18. Palomid 529 (P529)

    Catalog No. A10693
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    AKT 抑制剂
    Palomid 529是PI3K/Akt/mTOR途径的双重TORC1/2抑制剂,在血管生成和细胞增殖中具有广泛的活性。 了解更多
  19. YS-49

    Catalog No. A21198
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    PI3K/Akt activator
    YS-49 is a PI3K/Akt (a downstream target of RhoA) activator, to reduce RhoA/PTEN activation in the 3-methylcholanthrene-treated cells. 了解更多
  20. Histone Acetyltransferase Inhibitor II

    Catalog No. A12331
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    cell permeable p300 inhibitor
    Histone Acetyltransferase Inhibitor II is a potent and cell permeable p300 inhibitor, with an IC50 of 5 ?M; Histone Acetyltransferase Inhibitor II can be used in cancer research. 了解更多
  21. Src Inhibitor 1

    Catalog No. A12299
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    Src tyrosine kinase inhibitor
    Src Inhibitor 1 is a potent and selective dual site Src tyrosine kinase inhibitor with IC50 values of 44 nM for Src and 88nM for Lck. 了解更多
  22. CPA inhibitor

    Catalog No. A11369
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    CPA inhibitor
    CPA inhibitor is a potent inhibitor for carboxypeptidase A (CPA). 了解更多
  23. Cysteine Protease inhibitor

    Catalog No. A21048
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    cysteine protease inhibitor
    Cysteine Protease inhibitor is an inhibitor of cysteine protease. 了解更多
  24. PLpro inhibitor

    Catalog No. A21044
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    Plpro inhibitor
    PLpro inhibitor is a potent inhibitor of papain-like protease (PLpro) with IC50 of 2.6 uM. 了解更多
  25. Arginase inhibitor 1

    Catalog No. A21007
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    arginases I and II inhibitor
    Arginase inhibitor 1 is a potent inhibitor of human arginases I and II with IC50s of 223 and 509 nM, respectively. 了解更多
  26. Btk inhibitor 1 R enantiomer hydrochloride

    Catalog No. A21865
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    BTK inhibitor
    Btk inhibitor 1 R enantiomer hydrochloride (Ibrutinib analog hydrochloride) (Compound 14) is a covalent and irreversible Bruton??s tyrosine kinase (BTK) inhibitor and can be used in synthesis of Ibrutinib and ibrutinib-based activity-based probes (ABPs). 了解更多
  27. Btk inhibitor 1 (R enantiomer)

    Catalog No. A21861
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    BTK inhibitor
    Btk inhibitor 1 R enantiomer (Ibrutinib analog) (Compound 14) is a covalent and irreversible Bruton??s tyrosine kinase (BTK) inhibitor and can be used in synthesis of Ibrutinib and ibrutinib-based activity-based probes (ABPs). 了解更多
  28. Thrombin Inhibitor 2

    Catalog No. A21814
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    thrombin inhibitor
    Thrombin Inhibitor 2 is a small molecule direct thrombin inhibitor, extracted from US8541580B2. Thrombin Inhibitor 2 has antithrombotic activity. 了解更多
  29. GSK-3 inhibitor 1

    Catalog No. A21803
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    GSK-3 inhibitor
    GSK-3 inhibitor 1 is an inhibitor of GSK-3. 了解更多
  30. Glyoxalase I inhibitor free base

    Catalog No. A21721
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    Glyoxalase I (GLO1) inhibitor
    Glyoxalase I inhibitor (free base) is a potent Glyoxalase I (GLO1) inhibitor, candidate for anticancer agents. 了解更多
  31. USP7/USP47 inhibitor

    Catalog No. A21484
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    USP7/USP47 inhibitor
    USP7/USP47 inhibitor is a selective ubiquitin-specific protease 7/47 (USP7/USP47) inhibitor, with EC50s of 0.42 μM and 1.0 μM, respectively. 了解更多
  32. Mutant IDH1 inhibitor

    Catalog No. A21150
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    mutant IDH1 R132H inhibitor
    Mutant IDH1 inhibitor is a potent mutant IDH1 R132H inhibitor with IC50 of < 72 nM. 了解更多
  33. Mutant EGFR inhibitor

    Catalog No. A21144
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    EGFR inhibitor
    Mutant EGFR inhibitor is a potent and selective mutant EGFR inhibitor extracted from patent WO 2013014448 A1; inhibits EGFRL858R, EGFRExon 19 deletion and EGFRT790M. 了解更多
  34. Nav1.7 inhibitor

    Catalog No. A21141
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    Nav1.7 inhibitor
    Nav1.7 inhibitor is a potent Nav1.7 inhibitor. 了解更多
  35. HDACs/mTOR Inhibitor 1

    Catalog No. A13462
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    HDACs/mTOR Inhibitor 1
    HDACs/mTOR Inhibitor 1 is a dual Histone Deacetylases (HDACs) and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies. 了解更多
  36. IRAK inhibitor 4

    Catalog No. A11458
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    IRAK4 inhibitor
    IRAK inhibitor 4 is an interleukin-1 receptor associated kinase 4(IRAK4) inhibitor. 了解更多
  37. IRAK inhibitor 2

    Catalog No. A11456
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    interleukin-1 receptor associated kinase inhibitor
    IRAK inhibitor 2 is interleukin-1 receptor associated kinase inhibitor . 了解更多
  38. IRAK inhibitor 1

    Catalog No. A11455
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    IRAK-4 inhibitor
    IRAK inhibitor 1 is a potent IRAK-4 inhibitor with IC50 of 216 nM, is poorly active against JNK-1 and JNK-2 with IC50 of 3.801 μM, and >10 μM, respectively. 了解更多
  39. Glycolic acid oxidase inhibitor 1

    Catalog No. A13016
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    glycolate oxidase inhibitor
    Glycolic acid oxidase inhibitor 1 is a glycolate oxidase inhibitor, extracted from patent EP0021228A1, in Table IV. 了解更多
  40. Cot inhibitor-1

    Catalog No. A11366
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    COT/Tpl2 inhibitor
    Cot inhibitor-1 is a COT/Tpl2 inhibitor. 了解更多
  41. CNT2 inhibitor-1

    Catalog No. A12632
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    CNT2 Inhibitor
    CNT2 inhibitor-1 is a potent concentrative nucleoside transporter 2 Inhibitor (CNT2), with an IC50 of 640 nM for hCNT2. 了解更多
  42. mTOR inhibitor-2

    Catalog No. A13035
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    mTOR inhibitor
    mTOR inhibitor-2 is a highlt potent, selective and oral mTOR inhibitor with an IC50 of 7 nM. mTOR inhibitor-2 inhibits cellular phosphorylation of mTORC1 (pS6 and p4E-BP1) and mTORC2 (pAKT (S473)) substrates. 了解更多
  43. MK-2 Inhibitor III

    Catalog No. A13608
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    MAPKAP-K2 (MK-2) inhibitor
    MK-2 Inhibitor III (compound 16) is an orally active, selective, and ATP-competitive MAPKAP-K2 (MK-2) inhibitor with an IC50 of 0.85 nM. 了解更多
  44. Glyoxalase I inhibitor

    Catalog No. A11433
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    Glyoxalase I inhibitor
    Glyoxalase I inhibitor is a potent Glyoxalase I inhibitor, candidate for anticancer agents. 了解更多
  45. Malic enzyme inhibitor ME1

    Catalog No. A18564
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    ME1 inhibitor
    Malic enzyme inhibitor ME1 (ME1; compound 1) is a potent inhibitor of Malic enzyme (ME1) with an IC50 of 0.15 μM. 了解更多
  46. MARK4 inhibitor 1

    Catalog No. A18695
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    (MARK4 inhibitor
    MARK4 inhibitor 1 is a potent microtubule affinity-regulating kinase 4 (MARK4) inhibitor, with an IC50 of 1.54 μM. MARK4 inhibitor 1 inhibits cancer cell proliferation, metastasis and induces apoptosis. 了解更多
  47. URAT1 inhibitor 1

    Catalog No. A18720
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    URAT1 inhibitor
    URAT1 inhibitor 1 (1g) is a uric acid transporter 1 (URAT1) inhibitor, with an IC50 of 32 nM. URAT1 inhibitor 1 has potential to treat hyperuricemia associated with gout. 了解更多
  48. p32 Inhibitor M36

    Catalog No. A18846
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    p32 mitochondrial protein inhibitor
    p32 inhibitor M36 (M36) is a p32 mitochondrial protein inhibitor, which binds directly to p32 and inhibits p32 association with LyP-1. 了解更多
  49. HSP27 inhibitor J2

    Catalog No. A18874
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    HSP27 inhibitor
    HSP27 inhibitor J2 (J2) is a HSP27 inhibitor, which significantly induces abnormal HSP27 dimer formation and inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of the HSP27 and reducing a cell protection function thereof. 了解更多
  50. ROCK inhibitor-2

    Catalog No. A18912
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    ROCK1/ROCK2 inhibitor
    ROCK inhibitor-2 is a selective dual ROCK1 and ROCK2 inhibitor with IC50s of 17 nM and 2 nM, respectively. 了解更多

产品 1 到 50 共 5382个

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