Akt

Catalog No.Inhibitor Name Akt Akt1 Akt2 Akt3 Other Targets
A10003MK-2206 2HCl
***
***
**
A10709Perifosine
*
A11030GSK690693
****
***
***
PKCθ,PKCη,PrkX
A11246Ipatasertib
****
**
***
A11759AZD5363
****
***
***
ROCK2
A11024PF-04691502
****
PI3Kδ,PI3Kα,PI3Kγ
A10094AT7867
**
***
**
PKA,p70 S6K
A13210Triciribine
*
HIV-1
A11031CCT128930
****
p70 S6K,PKA
A11034A-674563
***
PKA,CDK2,GSK-3β
A11032PHT-427
*
PDK-1
A11286Akti-1/2
**
*
*
A15809Uprosertib
*
*
**
A16392Afuresertib
****
****
****
A12464AT13148
**
*
**
PKA,ROCK2,ROCK1
A14138Miltefosine
PI3K,PKC
A10453Honokiol
MEK
A12720TIC10 Analogue
ERK
A13460Deguelin
PI3K
A15903TIC10
ERK
A11287A-443654
****
A1359010-DEBC HCl
*
A16286ARQ-092 (Miransertib)
****
****
***

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

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  1. YS-49

    Catalog No. A21198
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    PI3K/Akt activator
    YS-49 is a PI3K/Akt (a downstream target of RhoA) activator, to reduce RhoA/PTEN activation in the 3-methylcholanthrene-treated cells. 了解更多
  2. SC79

    Catalog No. A15541
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    Akt phosphorylation activator
    SC79是AKT激活剂。SC79绑定到模仿PtdIns(3,4,5)P3的结合的Akt的plecktrin同源(PH)域,以诱导Akt的构象变化,从而增强磷酸化和激活。 了解更多

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